We have recently found an important problem when rearranging palettes or groups in Direct Selects.
If you save and reload after using the Arrange mode for palettes/groups, references in presets/cues could be out of sync.
This is new to v8 but is fixed in the upcoming v8.0.1.
In the meantime, avoid using Arrange mode for palettes or groups.
Note: If you are running multiple systems together, synchronization is also affected.