Bug Report - Patching - Road Hog 4 21 with DP8000 v4.2.0 (3753)

Currently doing a TV studio show with a Road Hog 4 21 with DP8000 on v4.2.0 (3753)

I have a show with generics and some movers across 10 universes. All patched and was working okay. 

I have had various odd things happen over the last two days of rehearsing. Channels I selected in the programmer wouldn't fade up; the desk top crashed and had to be re-started.

Today I tried to add two additional movers and 1 extra generic channel. They added ok, but the desk wouldn't let me patch them.

I re-booted the desk and the DP8000 but no change.

This is rather an urgent problem as we are in the middle of recording.