Yes and Yes! :) You will need a USB to VGA adapter of a certain make. It is available from your local dealer or you might find it in the open market. www.highend.com/products/controllers/RoadHogUSBtoVGA.asp
Well i have used 15,17 & 19 myself so i know they work just fine. As for the 22" i have not.
In the manual page 68, we state: Size ELO Model Description 17" ET1725L-7CWF-1-G AccuTouch 2216 series 17" ET1725L-7UWF-1 Accutouch 3000 series 17" ET1739L-8CWA-3-G IntelliTouch 2700 series 12" ET1229L-7UWA-1 Accutouch 3000 series 12" ET1215L-7CWA-1-G AccuTouch 1000 Series 12" ET1229L-8UWA-1 IntelliTouch 2500 Series 12" ET1229L-7CWA-1-ZBD-G AccuTouch 2216 series
And the models XX15L have reported to come back with good experiences.