CMA/PC/Vista problem

I can not open the program. I downloaded it today. It did not work. I went back, double checked I had the needed software mentioned on the HE sight. I also turned off active networks as discussed in this forum. I uninstalled, then re-installed after all the changes. Still no luck. What am I missing?
Problem is not just me or my computer. My fellow designer that is working on the same project tried for the first time today to open the CMA on his PC laptop, and had the same problem. At the time I did not ask what his O/S was.
Help will be greatly appricated
-Dee
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