Etc Eos lights stop responding!!!

Can you provide a bit more info about hardware of your Mac, your macOS version, nomad version, how you output (gadget, network) and the firmware version of your output device?

i use mac OS X sierra 10.12.5, Eos 2.5, gadget (don't know the firmware)

Any other information could also be useful. Does your mac go to sleep before this happens? Do you switch to other programs? Is there anything you have seen that makes it do it? Sleep and other programs taking processor time are the two big options I can think of. I know Nomad doesn't work very well unless it is the frontmost app. USB ports sleeping can cause issues with connected devices like the gadget. I disable sleep when using a computer for output purposes.